Primary tabs

Overcoming natural constraints to develop new vancomycin-type antibiotics

Lead organisation(s): 
Monash University
Project type: 
Research
Status: 
In progress
Summary: 
Glycopeptide antibiotics – which include vancomycin – are last-resort antibiotics used in the clinic to treat serious Gram-positive bacterial infections. In this project, my team are utilising a novel chemo-enzymatic formation route that we have pioneered to generate and explore the properties of new vancomycin derivatives. This will allow us to explore the structure/ function relationships of these crucial antibiotics and to overcome growing bacterial resistance against these compounds.
Timeframe: 
2016-2024
Are you the owner of this research? If you want to update or request removal please email amr.website@health.gov.au or use the Register update form.
Last updated: