New drugs for bad bugs: dual-functional therapies to treat resistant bacteria

In this project, my team is developing a new approach to tackling antimicrobial resistance that exploits alternate mechanisms to overcome bacterial infections through augmentation of host immune responses and removal of bacterial evasion mechanisms. Our simultaneous “drug-immune” therapies will provide highly synergistic bacterial killing utilising existing antibiotic therapeutics, thus underlining the feasibility of future clinical application of such approaches.